首页>>文献首页>>文献正文

18F-Containing Positron Emission Tomography Probe Conjugation Methodology for Biologics as Specific Binders for Tumors

tntplus 添加于 2018/1/13 10:31:46  596次阅读 | 0次推荐 | 0个评论

Molecular imaging can be used to evaluate the spatial–time change of the molecular biological phenomenon of the cell–molecule level in living bodies. Molecular imaging technology is expected to be applied in the fields of drug development, clinical diagnosis, and life science research. Specifically, positron emission tomography (PET) is a powerful non-invasive imaging technology for investigating physiological parameters in living animals using compounds labeled with PET radioisotopes as molecular probes. This review summarizes and compares various 18F-conjugation techniques that employ the chemical and enzymatic reactions of different types of tumor-targeting biological molecules such as peptides, proteins, antibodies, and nucleic acids.

作 者:Kenji Arimitsu, Hiroyuki Kimura, Yoshinari Arai, Kazuto Mochizuki, Masumi Taki.
期刊名称: Current Topics in Medicinal Chemistry
期卷页: 第16卷 第24期 2703 - 2724页
学科领域:医学科学 » 影像医学与生物医学工程 » 核医学
添加人是否为作者:
原文链接:http://www.eurekaselect.com/141226/article
DOI: 10.2174/1568026616666160413125948
ISBN:
关键词:
备 注:
文献笔记

   
导出选项:

评论 (0 个评论)

Page 1 of 1
<<<[1]>>>

举报 | Archiver | 科学网( 京ICP备07017567 )

GMT+8, 2011-2-15 11:31

Powered by ScienceNet.cn

Copyright © 2007- 科学时报社