首页>>文献首页>>文献正文

A modified fluorescein derivative with improved water-solubility for turn-on fluorescent determination of Hg2+ in aqueous and living cells

yanzhengquan 添加于 2017/4/4 16:26:19  85次阅读 | 0次推荐 | 0个评论

To improve the water-solubility of heavy-metal sensing materials, a modified fluorescein-based derivative, acryloyl fluorescein hydrazine (ACFH), was designed and developed by incorporating a non-hydrogen-bonding group into the conjugated molecule for weakening intermolecular hydrogen-bonding interactions. In neutral water environments, ACFH presented a fluorescence-enhancement performance at λmax = 512 nm in the presence of Hg2+, which could be visualized by naked-eyes. Under the optimized conditions, the linear range of Hg2+ detection was 1.0~100×10−9 mol•L−1 with a correlation coefficient of 0.9992 and a detection limit of 0.86×10−9 mol•L−1. The recognition mechanism was confirmed to be a stable and irreversible 1:1 five-member ring complex between ACFH and Hg2+ with a coordination constant of 3.36×109. ACFH would possess a potential application in detecting Hg2+ for biological assay with low cytotoxicity.

作 者: Shanyi Guang, Jiachan Tian, Gang Wei, Zhengquan Yan*, Hongfei Pan, Jihong Feng*, Hongyao Xu*
期刊名称: Talanta
期卷页: 2017 第170卷 第期 89-96页
学科领域:化学科学 » 分析化学 » 光谱分析
添加人是否为作者:
原文链接:http://www.sciencedirect.com/science/article/pii/S0039914017304022
DOI:
ISBN:
关键词:
全文地址: 下载
备 注:
文献笔记

 
导出选项:

评论 (0 个评论)

Page 1 of 1
<<<[1]>>>
发表评论:
验证码  
 

举报 | Archiver | 科学网( 京ICP备07017567 )

GMT+8, 2011-2-15 11:31

Powered by ScienceNet.cn

Copyright © 2007-2011 科学时报社