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DNA Fountain enables a robust and efficient storage architecture

zhpd55 添加于 2017/3/6 9:40:26  599次阅读 | 0次推荐 | 5个评论

DNA is an attractive medium to store digital information. Here we report a storage strategy, called DNA Fountain, that is highly robust and approaches the information capacity per nucleotide. Using our approach, we stored a full computer operating system, movie, and other files with a total of 2.14 × 106 bytes in DNA oligonucleotides and perfectly retrieved the information from a sequencing coverage equivalent to a single tile of Illumina sequencing. We also tested a process that can allow 2.18 × 1015 retrievals using the original DNA sample and were able to perfectly decode the data. Finally, we explored the limit of our architecture in terms of bytes per molecule and obtained a perfect retrieval from a density of 215 petabytes per gram of DNA, orders of magnitude higher than previous reports.

作 者:Yaniv Erlich, Dina Zielinski
期刊名称: Science
期卷页: 03 Mar 2017 第355卷 第6328期 950-954页
学科领域:生命科学 » 生物物理、生物化学与分子生物学 » 生物物理、生物化学与分子生物学研究的新方法与新技术
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原文链接:http://science.sciencemag.org/content/355/6328/950
DOI: 10.1126/science.aaj2038
ISBN:
关键词: DNA, polymerase chain reaction, DNA Fountain
全文地址: 下载
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