首页>>文献首页>>文献正文

Genome-Wide Scan for Bats and Dolphin to Detect Their Genetic Basis for New Locomotive Styles

zhangxia111 添加于 2012/12/13 14:10:16  798次阅读 | 0次推荐 | 0个评论

For most mammals, running is their major locomotive style, however, cetaceans and bats are two mammalian groups that have independently developed new locomotive styles (swimming and flying) from their terrestrial ancestors. In this study, we used a genome-wide comparative analysis in an attempt to identify the selective imprint of the development of new locomotive styles by cetaceans and bats to adapt to their new ecological niches. We found that an elevated proportion of mitochondrion-associated genes show evidence of adaptive evolution in cetaceans and on the common ancestral lineage leading to bats, compared to other terrestrial mammals. This result is consistent with the fact that during the independent developments of swimming and flying in these two groups, the changes of energy metabolism ratios would be among the most important factors to overcome elevated energy demands. Furthermore, genes that show evidence of sequence convergence or parallel evolution in these two lineages were overrepresented in the categories of energy metabolism, muscle contraction, heart, and glucose metabolism, genes that perform functions which are essential for locomotion. In conclusion, our analyses showed that on the dolphin and bat lineages, genes associated with locomotion not only both show a greater propensity to adaptively evolve, but also show evidence of sequence convergence, which likely reflects a response to a common requirement during their development of these two drastic locomotive styles.

作 者:Yong-Yi Shen
期刊名称: PLOS ONE
期卷页: 2012/11/6 第7卷 第11期 e46455~页
学科领域:生命科学 » 动物学 » 动物生理及行为学
添加人是否为作者:
原文链接:http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046455
DOI: 10.1371/journal.pone.0046455
ISBN: 1932-6203
关键词:
备 注:
文献笔记

   
导出选项:

评论 (0 个评论)

Page 1 of 1
<<<[1]>>>

举报 | Archiver | 科学网( 京ICP备07017567 )

GMT+8, 2011-2-15 11:31

Powered by ScienceNet.cn

Copyright © 2007- 科学时报社